The Anti-Hu CD44 FITC Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CD44. This antibody recognizes Human, Canine, and Porcine antigen. The Anti-Hu CD44 FITC Antibody has been validated for the following applications: Flow Cytometry.
Description
CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells